29–30 Oct 2018
Hotel Mercure Budapest
Europe/Budapest timezone

Life beyond the pixels: image analysis and machine learning for single-cell analysis

29 Oct 2018, 14:00
25m
Mátyás Hall (Groundfloor) (Hotel Mercure Budapest)

Mátyás Hall (Groundfloor)

Hotel Mercure Budapest

Krisztina körút 41-43. 1013 Budapest Hungary
Lecture

Speaker

Peter Horvath

Description

In this talk I will give an overview of the computational steps in the analysis of a single cell-based high-content screen. First, I will present a novel microscopic image correction method designed to eliminate vignetting and uneven background effects which, left uncorrected, corrupt intensity-based measurements. I will discuss methods capable of identifying cellular phenotypes based on features extracted from the image using deep learning and other advanced machine learning algorithms. For cases where discrete cell-based decisions are not suitable, we propose a method to use multi-parametric regression to analyze continuous biological phenomena. Finally single cell selection and isolation methods using machine learning will be discussed.

Primary author

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